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Epstein-Barr virus (EBV) is member of the human herpesvirus family and may be
opportunistic re-activations with various illnesses such as CFIDS and HIV. EBV
is the etiologic agent of acute infectious mononucleosis
. Most people (95%
) have EBV antibodies (meaning that
they have been exposed to the infection and have overcome it), so the EBV is
probably a re-activation of a past infection. Some pathogens (for example,
mycoplasma) are know n to reactivate
past viral infections.
Transmission
- Virus is secreted intermittently in the saliva of symptomatic carriers.
- EBV infects B lymphocytes and establishes a latent infection. The viral
genome enters the nucleus and persists in an episomal form. They transform the
B cell into an immortal, continuously dividing cell. A small number of these "EBV-transformed"
B cells circulate in the blood of healthy carriers. Their numbers are kept in
check by the host's immune response.

Symptoms
Symptoms include fever, generalized lymphadenopathy, sore throat, malaise,
tiredness, splenomegaly, hepatomegaly, abnormal liver function tests and
atypical lymphocytosis in the peripheral blood. The disease is self limiting,
but convalescence may be prolonged in some cases
.
Treatment
There is no official treatment for EBV. The following prescription drugs have
been tried with mixed results - generally faster recover but not elimination.
Acyclovir, valacyclovir
Azcytidine
NFkB (transcription factor)
inhibitors
EGFR (epidermal growth factor
receptor) inhibitors
The following non-prescription treatment has been tried with reports of
success, but no formal studies have been done.
Tumeric, Passion Flower (1/10 of
tumeric in effectiveness)

- Less or no effect: gingko, black cohosh, echinacea, kava-kava, saw
palmetto, angelica, wild yam, cat's claw, muira puama, feverfew, blueberry,
chasteberry, licorice, nettle, golden seal, pygeum, ginger, valerian and
hops.

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