Vitamin D
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Vitamin D is sometimes viewed as a non-issue for CFIDS except when following a protocol like that at marshallprotocol.com. It is my opinion that Vitamin D is an important adjunct for recovery from CFIDS (regardless of protocol). Boron may be an assistant to Vitamin D. I believe that Dr. Mercola, MD recommended optimal levels for Vitamin D is correct.
The following table indicates how much supplementation is needed (over a 6 month period) to reach these levels.
I would recommend keeping at 4000 IU/day (FDA deems that to be completely safe) instead of going to higher level -- and take a longer time to get there.
One International Unit (IU) of vitamin D is defined as the activity
of 0.025 μg of cholecalciferol.
Vitamin D is a generic term used to describe all substances that
exhibit the biological activity of cholecalciferol. These include:
Vitamin D2 is the form most commonly added to foods and dietary supplements (estimated to be 20% as effective as D3). Long term low vitamin 1,25D levels have significant health risks.
There are some studies suggesting that Vitamin D supplements may help CFS/FM
patients especially since it reduces inflammation For the most recent research, read "Vitamin
D status, 1,25-dihydroxyvitamin D3, and the immune system."
A recent article (Jan, 2005) in the Times (UK) is also worth reading. [quoted].
The chart below shows the actual distribution of types of Vitamin D in one group of women
From "Vitamin D status: effects on parathyroid hormone and 1,25-dihydroxyvitamin D in postmenopausal women" Am J Clin Nutr 2000;71:1577–81. A measure called "D-Ratio" has been proposed but never validated against real
data. The chart below shows the ratio on this typical population. Originally a
ratio of 4.0 was deemed significant
CFS/FM Literature on Vitamin D
Symptoms of Vitamin D Deficiency
Health Risk of low Vitamin D (especially 1,25D)
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Vitamin
D is a major controller of the entire
immune system. Depressing vitamin D will turn down (or off) the
immune system so you immune-response symptoms may disappear
-- however, it also means that the infections that you have will
no longer be fought and will rapidly reproduce. The reports of a
strong herx reaction from 1 mg of minocycline after reducing vitamin D
(when 200mg produced no herx before) appears to because of this
rapid unhindered growth of the infections. This turning off
of the immune system does not apply to just bacteria sensitive to
minocycline, but across the board to other infections: cancer virii,
viral etc. Suppress vitamin D levels have cause diabetes to appear in
test animals while their match sibling with adequate vitamin D never
developed diabetes.
